El Angiofibroma nasofaríngeo juvenil es un tumor benigno vascular (pero que tardíamente Se localiza en la pared posterolateral de la grita nasal a nivel del vínculo de la apófisis esfenoidal del hueso palatino. Esta localización conforma el. Nasal cavity, paranasal sinuses, nasopharynx – Nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally in the nasopharynx and nasal cavity, leading to manifestations such as nasal.

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Superior extension may occur, eroding orbital bones. Finally, numerous inflammatory cells such as mast cells and T-lymphocytes are seen. Angiofibroms sample comprised patients with a clinical and radiographic diagnosis of JNA with erosion of the skull base and minimal intracranial extension, meeting criteria for grade IIIa of the Radkowski classification.

Nasopharyngeal angiofibroma

National Center for Biotechnology InformationU. The mean operation time was min, and the mean bleeding volume was mL. Endoscopic surgery in treatment of juvenile nasopharyngeal angiofibroma. A typical staghorn type appearance is seen. Bone destruction negligible or limited to the sphenopalatine foramen II Invading the pterygopalatine fossa or the maxillary, ethmoid, or sphenoid sinus with bone destruction IIIa Invading the infratemporal fossa or orbital region without intracranial involvement IIIb Invading the infratemporal fossa or orbit jivenil intracranial extradural parasellar involvement IVa Intracranial intradural tumor without infiltration of the cavernous sinus, pituitary fossa or optic chiasm IVb Intracranial intradural tumor with infiltration of the cavernous sinus, pituitary fossa or optic jubenil.


In this study, immediate complications occurred in two patients who underwent surgery via endoscopic-guided external access. However, there is no consensus in the literature regarding the complications of nassal treatment of JNAs with intracranial extension.

Endoscopic treatment of lesions of the skull base is a branch of surgery that is currently undergoing rapid progress. Bony erosion of the nasal cavity, hard palate and pterygoid plates is also common.

This tumor originates in the lateral wall of the nasal cavity, close to the superior border of the sphenopalatine foramen. Although it is a rare neoplasm, accounting for less than 0.

Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. Paranasal sinuses, lateral pterygopalatine fossa; no residual vascularity. Direct intratumoral embolization of juvenile angiofibroma.

Nasopharyngeal angiofibroma: our experience and literature review

Of our 20 patients, only 2 underwent surgery without embolization, with these 2 showing significantly greater intraoperative bleeding than the 18 patients who underwent embolization. Angiofibromas originating outside the nasopharynx may appear as an intraoral mass in the retromolar or buccal space area.

Juvenile nasopharyngeal juvenik are benign but highly vascular tumours. As this tumor is aggressive and expansile, it invades adjacent structures causing further symptoms. Juvenile nasopharyngeal angiofibroma Nsaal is a benign neoplasm of the nasopharynx.

Open in a separate window. Intricate mixture of stellate and staghorn blood vessels with variable vessel wall thickness ranging from single layer of endothelium to variable smooth muscle coat Irregular fibrous stroma loose, edematous to dense, acellular Stromal cells are stellate fibroblasts with small pyknotic to large vesicular nuclei Larger vessels at base of lesion, smaller vessels with plump endothelial cells at growing edge of tumor Multinucleated stromal cells are common Mitotic figures are rare Minimal inflammation.


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No encapsulation was noted [ Figure 4 ]. Type III is a calabash-like massive tumor lobe in the middle cranial fossa.

The origin and development of JNA is not fully understood. The limitations of the present study should also be considered. Evaluation of the effectiveness of preoperative embolization in surgery for nasopharyngeal angiofibroma. IIIb Erosion of the skull base with extensive intracranial extension with or without cavernous sinus invasion. For all other comments, please send your remarks via contact us.

Treatment for Nasopharyngeal angiofibroma JNA is primarily surgical. It most commonly affects adolescent males and may grow into fissures of the skull and may spread to adjacent structures. Extraoral examination revealed normal appearing overlying skin. Current angikfibroma involves the hamartoma and vascular malformation theories.

The development of minimally invasive techniques has led to the increased use of endoscopic surgery for the treatment of nasopharyngeal angiofibroma 21making it ideal for tumors confined to the nasopharynx, nasal cavity, and sphenoid sinus with minimal extension into the pterygopalatine fossa 10,12,13,15,18,